Immunoloy and Virology Lab

•     Silva BBI, Urzo MLR, Encabo JR, Simbulan AM, Lunaria AJD, Sedano SA, Hsu KC, Chen CC, Tyan YC, Chuang KP:              Pigeon Circovirus over Three Decades of Research: Bibliometrics, Scoping Review, and Perspectives. Viruses
      2022, 14(7).

•     Huang YF, Ho TC, Chang CC, Shen DH, Chan HP, Chuang KP, Tyan YC, Yang MH: A Rare Adverse Effect of the COVID-19 Vaccine on Autoimmune Encephalitis. Vaccines (Basel) 2022, 10(7).

•    Ho TC, Chang CC, Chan HP, Chung TW, Shu CW, Chuang KP, Duh TH, Yang MH, Tyan YC: Hydrogels: Properties and
       Applications in Biomedicine. Molecules 2022, 27(9).

      Chang CC, Ho TC, Lien CY, Shen DH, Chuang KP, Chan HP, Yang MH, Tyan YC: The Effects of Prior Mammography
      Screening on the Performance of Breast Cancer Detection in Taiwan. Healthcare (Basel) 2022, 10(6).

  • Tzu-Chuan Ho, Yi-Ming Arthur Chen, Hung-Pin Chan, Chin-Chuan Chang, Kuo-Pin Chuang, Che-Hsin Lee, Cheng-Hui Yuan, Yu-Chang Tyan and Ming-Hui Yang (2021) The Effects of Heterologous Immunization with Prime-Boost COVID-19 Vaccination against SARS-CoV-2. Vaccines 9 (10), 1163. IF4.422

  • Ching-Chi Chang, Benji Brayan I. Silv , Huai-Ying Huang , Ching-Yi Tsai, Ronilo Jose D. Flores, Lemmuel L. Yu-Chang Tyan, Ming-An Tsai , Gail Everette M. Catulin, Kuo-Pin Chuang ,* and Jenq-Lin Yang* (2021) Development and Validation of KASP Assays for the Genotyping of Racing Performance-Associated Single Nucleotide Polymorphisms in Pigeons. Genes 12,1381. IF 4.04 (co-corresponding author, Q2)

  • Huai-Ying Huang, Benji Brayan I Silva, Shen-Pang Tsai, Ching-Yi Tsai, Yu-Chang Tyan, Tzu-Che Lin, Ronilo Jose D Flores, Kuo-Pin Chuang. (2021). Immunogenicity and Protective Activity of Pigeon Circovirus Recombinant Capsid Protein Virus-Like Particles (PiCV rCap-VLPs) in Pigeons (Columba livia) Experimentally Infected. Vaccines 9(2),98 Q1, IF:4.4

  • Ming-Hui Yang, Yi-Ming Arthur Chen, Shan-Chen Tu, Pei-Ling Chi, Kuo-Pin Chuang, Chin-Chuan Chang, Chiang-Hsuan Lee, Yi-Ling Chen, Che-Hsin Lee, Cheng-Hui Yuan, Yu-Chang Tyan. (2021). Utilizing an Animal Model to Identify Brain Neurodegeneration-Related Biomarkers in Aging. International journal of molecular sciences, 22(6), 3278.

  • Tzu-Chuan Ho, Chin-Chuan Chang, Hung-Pin Chan, Ying-Fong Huang, Yi-Ming Arthur Chen, Kuo-Pin Chuang, Che-Hsin Lee, Cheng-Hui Yuan, Yu-Zhen Deng, Ming-Hui Yang, Yu-Chang Tyan. (2021) Pulmonary Findings of [18F] FDG PET/CT Images on Asymptomatic COVID-19 Patients. Pathogens, 10 (7), 839.

  • Ho, T.-C., Wang, Y.-H., Chen, Y.-L., Tsai, W.-C., Lee, C.-H., Chuang, K.-P., .Yang, M.-H. (2021). Chloroquine and Hydroxychloroquine: Efficacy in the Treatment of the COVID-19. Pathogens, 10(2), 217.

  • Yang, M.-H., Chen, Y.-M. A., Tu, S.-C., Chi, P.-L., Chuang, K.-P., Chang, C.-C., Yuan, C.-H. (2021). Utilizing an Animal Model to Identify Brain Neurodegeneration-Related Biomarkers in Aging. International journal of molecular sciences, 22(6), 3278.

  • .Ching-Yi Tsai , Shao-Yang Hu , Harvey M Santos , Gail Everette M Catulin ,  Lemmuel L Tayo , Kuo Pin Chuang, (2021) Probiotic supplementation containing Bacillus velezensis enhances expression of immune regulatory genes against pigeon circovirus in pigeons (Columba livia).J Appl Microbiology. Accepted (SCI, Rnaking, Q1, IF:3.27)

  • Santos, H.M., Chen, C.C., Tsai, C.-Y., Hsish, Y.C., Chung, F.C., Tyan, Y.-C., Tayo, L.L., Chuang, K.P., 2020a. Influence of pigeon interferon alpha (PiIFN-α) on pigeon circovirus (PiCV) replication and cytokine expression in Columba livia. Veterinary Microbiology 242, 108591.

  • Santos, H.M., Tsai, C.-Y., Catulin, G.E.M., Trangia, K.C.G., Tayo, L.L., Liu, H.-J., Chuang, K.P., 2020b. Common Bacterial, Viral and Parasitic Diseases in Pigeons (Columba livia): A Review of Diagnostic and Treatment Strategies. Veterinary Microbiology, 108779.

  • Santos, H.M., Tsai, C.-Y., Maquiling, K.R.A., Tayo, L.L., Mariatulqabtiah, A.R., Lee, C.-W., Chuang, K.P., 2020c. Diagnosis and potential treatments for acute hepatopancreatic necrosis disease (AHPND): a review. Aquaculture International 28, 169-185.

  • Santos, H.M., Tsai, C.Y., Yanuaria, C.A.S., Tayo, L.L., Vo, D.D., Mariatulqabtiah, A.R., Chuang, K.P., 2019. Effects of sodium alginate‐fed Pacific white shrimps, Litopenaeus vannamei, on Toll‐like receptors and Vibrio alginolyticus infection. Aquaculture Research 50, 1384-1392.

  • Tsai, C.-Y., Santos, H.M., Hu, S.-Y., Sang, C.Y., Yanuaria, C.A.S., Lola, E.N.G., Tayo, L.L., Nitura, K.M.A., Liu, C.H., Chuang, K.P., 2019. LpxD gene knockout elicits protection to Litopenaeus vannamei, white shrimp, against Vibrio parahaemolyticus infection. Aquaculture International 27, 1383-1393.

  • Zhang, R.-Z., Tsai, S.-S., Chao, H.-R., Shieh, Y.-C., Chuang, K.-P., 2016. Innovation of a new virus-like nanoparticle vaccine system for the specific aerosol relative disease. Aerosol and Air Quality Research 16, 2421-2427.

  • Gou, Y.-Y., Lin, S., Que, D.E., Tayo, L.L., Lin, D.-Y., Chen, K.-C., Chen, F.-A., Chiang, P.-C., Wang, G.-S., Hsu, Y.-C., 2016a. Estrogenic effects in the influents and effluents of the drinking water treatment plants. Environmental Science and Pollution Research 23, 8518-8528

  • Gou, Y.-Y., Que, D.E., Chuang, C.-Y., Chao, H.-R., Shy, C.-G., Hsu, Y.-C., Lin, C.-W., Chuang, K.P., Tsai, C.-C., Tayo, L.L., 2016b. Dust levels of polybrominated diphenyl ethers (PBDEs) and polybrominated dibenzo-p-dioxins/furans (PBDD/Fs) in the Taiwanese elementary school classrooms: Assessment of the risk to school-age children. Science of The Total Environment 572, 734-741.

  • Huang, W.-R., Chiu, H.-C., Liao, T.-L., Chuang, K.-P., Shih, W.-L., Liu, H.-J., 2015a. Avian reovirus protein p17 functions as a nucleoporin Tpr suppressor leading to activation of p53, p21 and PTEN and inactivation of PI3K/AKT/mTOR and ERK signaling pathways. PLoS One 10.

  • Chou, H.-M., Kao, C.-C., Chuang, K.P., Lin, C., Shy, C.-G., Chen, R.-F., Tsai, C.-C., Chuang, C.-Y., Cheng, Y.-C., Chen, C.-C., 2015. Levels of polybrominated diphenyl ethers in air-conditioner filter dust used to assess health risks in clinic and electronic plant employees. Aerosol and Air Quality Research 16, 184-194.

  • Huang, W.-R., Chiu, H.-C., Liao, T.-L., Chuang, K.-P., Shih, W.-L., Liu, H.-J., 2015b. Avian reovirus protein p17 functions as a nucleoporin Tpr suppressor leading to activation of p53, p21 and PTEN and inactivation of PI3K/AKT/mTOR and ERK signaling pathways. PLoS One 10, e0133699.

  • Chuang, K., 2015. Development of a loop-mediated isothermal amplification method for rapid detection of beak and feather disease virus in parrots. Arch Clin Microbiol 7, 1.

  • Liao, P.-C., Wang, K.-K., Tsai, S.-S., Liu, H.-J., Huang, B.-H., Chuang, K.-P., 2015. Recurrent positive selection and heterogeneous codon usage bias events leading to coexistence of divergent pigeon circoviruses. Journal of General Virology 96, 2262-2273.

  • Shen, S.Y., Chang, W.C., Yi, H.H., Tsai, S.-S., Liu, H.J., Liao, P.-C., Chuang, K.P., 2015. Development of a subunit vaccine containing recombinant chicken anemia virus VP1 and pigeon IFN-γ. Veterinary immunology and immunopathology 167, 200-204.

  • Shy, C.-G., Hsu, Y.-C., Shih, S.-I., Chuang, K.P., Lin, C.-W., Wu, C.-W., Chuang, C.-Y., Chao, H.-R., 2015. Indoor level of polybrominated diphenyl ethers in the home environment and assessment of human health risks. Aerosol Air Qual. Res 15, 1494-1505.

  • Tsai, S.-S., Chen, L.-J., Shih, C.-Y., Chang, T.-C., Chiou, M.-T., Chuang, K.P., 2015. Joint Lesions in Taiwan Native Colored Broiler Chicken with Natural and Experimental Staphylococcus aureus or S. cohnii Infection. Taiwan Veterinary Journal 41, 237-244.

  • Tsai, S.S., Chang, Y.L., Huang, Y.L., Liu, H.J., Ke, G.M., Chiou, C.J., Hsieh, Y.C., Chang, T.C., Cheng, L.T., Chuang, K.P., 2014. Development of a loop-mediated isothermal amplification method for rapid detection of pigeon circovirus. Archives of virology 159, 921-926.

  • HUANG, T.C., CHANG, J.Y., LIU, H.J., TSAI, S.S., CHANG, T.C., HO, C.T., Chuang, K.P., 2013. Eriodictyol decreases reactive oxygen species production and inhibits p47phox clustering and translocation in monocytes. Journal of Food Biochemistry 37, 418-424.

  • Xu, X.-G., Zhao, H.-N., Zhang, Q., Ding, L., Li, Z.-C., Li, W., Wu, H.-Y., Chuang, K.-P., Tong, D.-W., Liu, H.-J., 2012. Oral vaccination with attenuated Salmonella enterica serovar Typhimurium expressing Cap protein of PCV2 and its immunogenicity in mouse and swine models. Veterinary microbiology 157, 294-303.

  • Ke, G.M., Chuang, K.P., Chang, C.D., Lin, M.Y., Liu, H.J., 2010. Analysis of sequence and haemagglutinin activity of the HN glycoprotein of Newcastle disease virus. Avian pathology 39, 235-244.

  • Huang, T.-C., Teng, K.C., Liou, Y.-Y., Ho, C.-T., Liu, H.-J., Chuang, K.P., 2010a. Diallyl disulphide, but not diallyl sulphide, increases leucocyte function-associated antigen-1 expression and cellular adhesion in monocytes. Food chemistry 120, 113-120.

  • Huang, T.-C., Tsai, S.-S., Liu, L.-F., Liu, Y.L., Liu, H.-J., Chuang, K.P., 2010b. Effect of Arctium lappa L. in the dextran sulfate sodium colitis mouse model. World journal of gastroenterology: WJG 16, 4193.

  • Huang, T.-C., Tseng, K.Y., Tsai, S.-S., Liu, H.-J., Ho, C.-T., Lin, H.Y., Cheng, L.T., Chuang, K.P., 2010c. Eriodictyol decreases very late antigen-4 (VLA-4) expression, cellular adhesion, and migration through an NFκB-dependent pathway in monocytes. Journal of Functional Foods 2, 263-270.

  • Yang, Z.-J., Wang, C.-Y., Lee, L.-H., Chuang, K.-P., Lien, Y.-Y., Yin, H.-S., Tong, D.-W., Xu, X.-G., Liu, H.-J., 2010. Development of ELISA kits for antibodies against avian reovirus using the σC and σB proteins expressed in the methyltropic yeast Pichia pastoris. Journal of virological methods 163, 169-174.

  • Lin, F.L., Chang, C.I., Chuang, K.P., Wang, C.Y., Liu, H.J., 2010. Advanced glycation end products down-regulate gap junctions in human hepatoma SKHep 1 cells via the activation of Src-dependent ERK1/2 and JNK/SAPK/AP1 signaling pathways. Journal of agricultural and food chemistry 58, 8636-8642.

  • Huang, T.C., Lin, Y.T., Chuang, K.P., 2010d. Carvacrol has the priming effects of reactive oxygen species (ROS) production in C6 glioma cells. Food and agricultural immunology 21, 47-55.

  • Liu, S.Y., Tsai, M.Y., Chuang, K.P., Huang, Y.F., Shieh, C.C., 2008. Ligand binding of leukocyte integrin very late antigen‐4 involves exposure of sulfhydryl groups and is subject to redox modulation. European journal of immunology 38, 410-423.

  • Chuang, K.-P., Huang, Y.-F., Hsu, Y.-L., Liu, H.-S., Chen, H.-C., Shieh, C.-C., 2004. Ligation of lymphocyte function-associated antigen-1 on monocytes decreases very late antigen-4-mediated adhesion through a reactive oxygen species-dependent pathway. Blood 104, 4046-4053.

  • Chuang, K.P., Tsai, W.S., Wang, Y.J., Shieh, C.C., 2003. Superoxide activates very late antigen‐4 on an eosinophil cell line and increases cellular binding to vascular cell adhesion molecule‐1. European journal of immunology 33, 645-655

  • Chuang, K.P., Tsai, W.S., Wang, Y.J., Shieh, C.C., 2003. Superoxide activates very late antigen‐4 on an eosinophil cell line and increases cellular binding to vascular cell adhesion molecule‐1. European journal of immunology 33, 645-655.

  • Kuo, Y.M., Chen, H.H., Shieh, C.C., Chuang, K.P., Cherng, C.G., Yu, L., 2003. 4‐Hydroxytamoxifen attenuates methamphetamine‐induced nigrostriatal dopaminergic toxicity in intact and gonadetomized mice. Journal of neurochemistry 87, 1436-1443.